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June 27, 2023
財經

多家藥商研究減重口服藥 禮來公布最新試驗檢果

糖尿病藥物因具有減重效果大受歡迎,促使多家藥商尋求研究口服減重藥片,這一可能達數十億元的潛在商機已吸引禮來藥廠(Eli Lilly)、丹麥製藥公司諾和諾德(Novo Nordisk)、輝瑞 等大型製藥商投入,成為藥物研究最熱門的領域之一。

禮來公司近期發表在《新英格蘭醫學雜志》上的二期臨床試驗結果顯示,服用這種名為orforlipron的口服減重藥物的參與者在36周後平均減輕了9.4%至14.7%的體重,具體取決於給藥劑量。

該研究的主要作者肖恩·沃頓博士是沃頓醫學診所的減肥專家,該診所專注於安大略省伯靈頓的減肥和糖尿病管理。

沃頓說,像口服西馬魯肽一樣,orforlipron也需要每天早上服用。然而,與口服西馬魯肽不同,orforlipron可以在進食後30分鐘內服用。

據醫學網站報道,禮來公司正在開展orforlipron的三期臨床試驗。到目前為止,口服減肥藥都沒有顯示出像禮來公司的注射減肥用的療效。

禮來注射減肥用”替西帕肽”的試驗顯示,72周後患者體重平均減輕22.5%。

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