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July 22, 2021
Uncategorized

Moderna疫苗全部受試者產生抗體

週一,Moderna公司宣布備受關注的新冠疫苗人體實驗取得積極進展,所有接受實驗的人均產生了抗體。

Moderna共對45人進行了早期測試。被試者分為3組,每組15人。公司宣布,這45人全部產生了抗體。實驗對每組分別注射了25微克(microgram)、100微克、250微克劑量的疫苗。分兩次注射在上臂,每次間隔28天。在第43天,也就是第二次注射後的兩週後,注射25微克的實驗組、體內產生的抗體達到了那些從疾病中康復的人的血液樣本中的含量水平。而注射了100微克的實驗組體內產生的抗體則遠超康復患者體內的抗體水平。注射了250微克的實驗組數據尚未公開。

另外,公司稱,在實驗組中至少8個參與者(4位來自25微克、另外4位來自100微克)身上產生了「中和抗體」(Neutralizing Antibodies),且水平高於新冠康復患者體內的水平。專家此前曾表示中和抗體對人體能產生保護作用非常重要。

Moderna是第一家公佈人體實驗數據的公司,該結果屬於一期實驗。在二期,Moderna預計會納入600名試驗者,預期在7月進行三期實驗。如果實驗證明有效並安全,預計2021年可以進入市場。

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