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July 22, 2021
Uncategorized

莫德納疫苗受試者全產生抗體 月底展開最後試驗

美國生技大廠莫德納公司(Moderna Inc.)研發的新冠狀病毒疾病實驗性疫苗,傳出進展順利的好消息。在受試45人身上全都出現抗體反應,即將於本月27日展開臨床試驗的最後階段。

據「新英格蘭醫學期刊」14日刊登的研發成果,在第一期安全試驗中的所有受試者體內都產生抗體,該疫苗產生的病毒中和抗體數量,相當於染疫並痊癒者體內抗體數量的中上水準;儘管加速產生病毒中和抗體並不能證明疫苗有效,仍被視為試驗初期的重要進展。

全國過敏和傳染病研究所(NIAID)研究人員的報告也指出,該疫苗通報讓大部分受試者出現的副作用,也沒有嚴重到無法進一步受試的程度。接受三劑疫苗中第二劑接種的患者中,超過半數出現輕度至中度疲勞、發冷、頭痛以及肌肉疼痛等症狀,而第二次接種第二劑疫苗的受試者中也有40%發燒;接種劑量最高的14位受試者中,有三位出現嚴重副作用,但這種劑量並未在較大規模試驗中使用。

研究人員表,疫苗出現副作用的機率這麼高相當「不尋常」,但其產生的抗體數量「真的很振奮人心」;如果研究在大型試驗中證明衡量的項目正確,該疫苗可望有效。

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