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July 22, 2021
Uncategorized

牛津大學疫苗初期臨床測試者均有免疫反應

英國牛津大學和英國阿斯特捷利康藥廠(AstraZeneca)合作研發的新型冠狀病毒實驗疫苗,號稱是目前全球臨床試驗進展最快、最先進的疫苗,已進入人體臨床三期階段。20日又傳出好消息,根據公佈在重量級醫學期刊《刺胳針上的報告》,該疫苗在初期接受測試的1100人均成功產生免疫反應。

牛津與阿斯特捷利康共同開發名為 ChAdOx1 的新冠疫苗,在第一階段的試驗中,對於 1000 名自願參與者進行測試,並且成功引發了雙重免疫反應。在注射疫苗 28 天之後,受試者除了產生中和抗體之外,亦動員了免疫系統中的 T 細胞(T-cells)。有越來越多的證據顯示,T 細胞對於防禦新冠病毒相當重要。

牛津大學詹納研究所(Jenner Institute)教授希爾(Adrian Hill)指出,由於人體試驗結果出現了強烈的免疫反應,顯示牛津疫苗對抗新冠病毒的可能性提高,但目前尚未有任何保證,希爾亦表示,未來將會持續觀察受試者,並希望能夠在接下來幾週於美國進行人體試驗。

世界衛生組織 (WHO)表示,目前全球共有 160 個新冠疫苗,分別處於不同的開發階段。除了牛津疫苗之外,美生技公司 Moderna 於上週宣布,第一期人體試驗結果顯示,45 名受試者都在體內產生了強烈的免疫反應,接下來這款疫苗預計將在 7 月 27 日展開大規模臨床試驗。

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